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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UHRF1
All Species:
18.18
Human Site:
Y418
Identified Species:
40
UniProt:
Q96T88
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96T88
NP_001041666.1
793
89814
Y418
T
I
V
P
S
N
H
Y
G
P
I
P
G
I
P
Chimpanzee
Pan troglodytes
XP_001139655
792
89650
Y418
T
I
V
P
S
N
H
Y
G
P
I
P
G
I
P
Rhesus Macaque
Macaca mulatta
XP_001082893
795
89906
Y420
T
I
V
P
S
N
H
Y
G
P
I
P
G
I
P
Dog
Lupus familis
XP_868468
799
89797
Y421
T
I
V
P
S
N
H
Y
G
P
I
P
G
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDF2
782
88285
R399
A
S
A
T
S
S
S
R
R
D
W
G
K
G
M
Rat
Rattus norvegicus
Q7TPK1
774
87430
R391
A
S
A
T
S
S
S
R
R
D
W
G
K
G
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507628
851
95788
Y486
T
I
V
P
S
N
H
Y
G
P
I
P
G
V
P
Chicken
Gallus gallus
XP_418269
760
84868
R379
A
S
A
N
S
S
S
R
R
D
W
G
K
G
M
Frog
Xenopus laevis
NP_001129236
772
86955
Q392
A
S
A
N
S
S
S
Q
R
D
W
G
K
G
M
Zebra Danio
Brachydanio rerio
NP_998242
775
87072
Q391
A
S
A
S
S
S
S
Q
R
D
W
G
K
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791602
653
73619
G290
I
V
P
P
N
H
F
G
A
V
P
G
I
H
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.2
88.1
N.A.
74.9
75.7
N.A.
53.3
71.5
66.5
68
N.A.
N.A.
N.A.
N.A.
47.5
Protein Similarity:
100
99.7
98.8
92.7
N.A.
87
87.5
N.A.
68.5
82
79.9
83
N.A.
N.A.
N.A.
N.A.
62.1
P-Site Identity:
100
100
100
100
N.A.
6.6
6.6
N.A.
93.3
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
13.3
13.3
N.A.
100
13.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
46
0
46
0
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
46
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
46
0
0
55
46
46
0
% G
% His:
0
0
0
0
0
10
46
0
0
0
0
0
0
10
0
% H
% Ile:
10
46
0
0
0
0
0
0
0
0
46
0
10
37
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
46
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
46
% M
% Asn:
0
0
0
19
10
46
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
55
0
0
0
0
0
46
10
46
0
0
46
% P
% Gln:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
28
46
0
0
0
0
0
0
% R
% Ser:
0
46
0
10
91
46
46
0
0
0
0
0
0
0
0
% S
% Thr:
46
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
46
0
0
0
0
0
0
10
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
46
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
46
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _